Hydroxine

Hydroxine Brand names, Hydroxine Analogs

Hydroxine Brand Names Mixture

No information avaliable

Hydroxine Chemical_Formula

C₂₁H₂₇ClN₂O₂

Hydroxine RX_link

http://www.rxlist.com/cgi/generic/hydrox.htm

Hydroxine fda sheet

Hydroxine msds (material safety sheet)

Hydroxine MSDS

Hydroxine Synthesis Reference

Moren; U.S. Pat. 2,899,436 (1959)

Hydroxine Molecular Weight

374.904 g/mol

Hydroxine Melting Point

190 ^oC

Hydroxine H₂O Solubility

< 700 mg/mL

Hydroxine State

Solid

Hydroxine LogP

3.036

Hydroxine Dosage Forms

Capsule; Liquid; Solution; Syrup

Hydroxine Indication

For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria.

Hydroxine Pharmacology

Hydroxyzine, a piperazine antihistamine structurally related to buclizine, cyclizine, and meclizine, is used to treat histamine-mediated pruritus or pruritus due to allergy, nausea and vomiting, and, in combination with an opiate agonist, anxiolytic pain. Hydroxyzine is also used as a perioperative sedative and anxiolytic and to manage acute alcohol withdrawal. Hydroxyzine's active metabolite, cetirizine, is also used as an H₁-antagonist.

Hydroxine Absorption

Rapidly absorbed from the gastrointestinal tract

Hydroxine side effects and Toxicity

Oral, rat LD₅₀: 950 mg/kg. Symptoms of overexposure include hypersedation.

Hydroxine Patient Information

Hydroxine Organisms Affected

Humans and other mammals