Masmoran
Brand names,
Masmoran
Analogs
Masmoran
Brand Names Mixture
Masmoran
Chemical_Formula
C21H27ClN2O2
Masmoran
RX_link
http://www.rxlist.com/cgi/generic/hydrox.htm
Masmoran
fda sheet
Masmoran
msds (material safety sheet)
Masmoran
Synthesis Reference
Moren; U.S. Pat. 2,899,436 (1959)
Masmoran
Molecular Weight
374.904 g/mol
Masmoran
Melting Point
190 oC
Masmoran
H2O Solubility
< 700 mg/mL
Masmoran
State
Solid
Masmoran
LogP
3.036
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Dosage Forms
Capsule; Liquid; Solution; Syrup
Masmoran
Indication
For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria.
Masmoran
Pharmacology
Hydroxyzine, a piperazine antihistamine structurally related to buclizine, cyclizine, and meclizine, is used to treat histamine-mediated pruritus or pruritus due to allergy, nausea and vomiting, and, in combination with an opiate agonist, anxiolytic pain. Hydroxyzine is also used as a perioperative sedative and anxiolytic and to manage acute alcohol withdrawal. Hydroxyzine's active metabolite, cetirizine, is also used as an H1-antagonist.
Masmoran
Absorption
Rapidly absorbed from the gastrointestinal tract
Masmoran
side effects and Toxicity
Oral, rat LD50: 950 mg/kg. Symptoms of overexposure include hypersedation.
Masmoran
Patient Information
Masmoran
Organisms Affected
Humans and other mammals