Hydroxyzine Base

Hydroxyzine Base Brand names, Hydroxyzine Base Analogs

Hydroxyzine Base Brand Names Mixture

No information avaliable

Hydroxyzine Base Chemical_Formula

C₂₁H₂₇ClN₂O₂

Hydroxyzine Base RX_link

http://www.rxlist.com/cgi/generic/hydrox.htm

Hydroxyzine Base fda sheet

Hydroxyzine Base msds (material safety sheet)

Hydroxyzine_Base MSDS

Hydroxyzine Base Synthesis Reference

Moren; U.S. Pat. 2,899,436 (1959)

Hydroxyzine Base Molecular Weight

374.904 g/mol

Hydroxyzine Base Melting Point

190 ^oC

Hydroxyzine Base H₂O Solubility

< 700 mg/mL

Hydroxyzine Base State

Solid

Hydroxyzine Base LogP

3.036

Hydroxyzine Base Dosage Forms

Capsule; Liquid; Solution; Syrup

Hydroxyzine Base Indication

For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested. Useful in the management of pruritus due to allergic conditions such as chronic urticaria.

Hydroxyzine Base Pharmacology

Hydroxyzine, a piperazine antihistamine structurally related to buclizine, cyclizine, and meclizine, is used to treat histamine-mediated pruritus or pruritus due to allergy, nausea and vomiting, and, in combination with an opiate agonist, anxiolytic pain. Hydroxyzine is also used as a perioperative sedative and anxiolytic and to manage acute alcohol withdrawal. Hydroxyzine's active metabolite, cetirizine, is also used as an H₁-antagonist.

Hydroxyzine Base Absorption

Rapidly absorbed from the gastrointestinal tract

Hydroxyzine Base side effects and Toxicity

Oral, rat LD₅₀: 950 mg/kg. Symptoms of overexposure include hypersedation.

Hydroxyzine Base Patient Information

Hydroxyzine Base Organisms Affected

Humans and other mammals