Phenformin
Phenformin Brand names, Phenformin Analogs
- Azucaps
- Beta-Pebg
- Beta-Phenethybiguanide
- Beta-Phenethylbiguanide
- Cronoformin
- D Bretard
- DBI
- DB Comb
- DB-Retard
- DBI Monohydrochloride
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenformina
- Fenformina [Inn-Spanish]
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Meltrol-50
- N-Phenethylbiguanide Hydrochloride
- Normoglucina
- Pedg
- Phenethylbiguanide Hydrochloride
- Phenethyldiguanide
- Phenformin HCl
- Phenformin Hydrochloride
- Phenformine
- Phenformine HCl
- Phenformine [Inn-French]
- Phenforminum [Inn-Latin]
- Phenformix
- Phenoformine Hydrochloride
- Phenylethylbiguanide
- Retardo
Phenformin Brand Names Mixture
- No information avaliable
Phenformin Chemical_Formula
C10H15N5
Phenformin RX_link
No information avaliable
Phenformin fda sheet
Phenformin msds (material safety sheet)
Phenformin Synthesis Reference
Shapiro, Freedman, U.S. pats. 2,961,377, 3,057,780 (1960, 1962 both to U.S.V.)
Phenformin Molecular Weight
205.26 g/mol
Phenformin Melting Point
175-178 oC
Phenformin H2O Solubility
210 mg/mL
Phenformin State
Solid
Phenformin LogP
0.759
Phenformin Dosage Forms
No information avaliable
Phenformin Indication
For the reatment of type II diabetes mellitus.
Phenformin Pharmacology
Used to treat diabetes, phenformin is a biguanide (contains 2 guanidino groups) hypoglycemic agent with actions and uses similar to those of metformin (Glucophage). Both drugs work by (1) decreasing the absorption of glucose by the intestines, (2) decreasing the production of glucose in the liver, and by (3) increasing the body's ability to use insulin more effectively. More specifically, phenformin improves glycemic control by improving insulin sensitivity. Phenformin is generally considered to be associated with an unacceptably high incidence of actic acidosis. In general biguanides should be used only in stable type II diabetics who are free of liver, kidney and cardiovascular problems and who cannot be controlled with diet.
Phenformin Absorption
No information avaliable
Phenformin side effects and Toxicity
No information avaliable
Phenformin Patient Information
No information avaliable
Phenformin Organisms Affected
Humans and other mammals
