Jestryl
Jestryl Brand names, Jestryl Analogs
- CB
- Carbachol USP27
- Carbachol chloride
- Carbachol hydrochloride
- Carbacholin
- Carbacholine
- Carbacholine chloride
- Carbacolina
- Carbaminocholine chloride
- Carbaminoylcholine chloride
- Carbamiotin
- Carbamoylcholine chloride
- Carbamoylcholine-hydrochloride
- Carbamylcholine chloride
- Carbastat
- Carbastat intraocular
- Carbochol
- Carbocholin
- Carbocholine
- Carboptic
- Carbyl
- Carcholin
- Choline carbamate chloride
- Choline chloride carbamate
- Choline chloride, carbamoyl-
- Choline chlorine carbamate
- Choline, chloride, carbamate
- Coletyl
- Doryl
- Isopto Carbachol
- Jestryl
- Karbachol
- Karbamoylcholin chlorid
- Lentin
- Lentine
- Miostat
- Mistura C
- Moryl
- P. V. Carbachol
- Rilentol
- Vasoperif
Jestryl Brand Names Mixture
- No information avaliable
Jestryl Chemical_Formula
C6H15N2O2+
Jestryl RX_link
http://www.rxlist.com/cgi/generic2/carbachol.htm
Jestryl fda sheet
Jestryl msds (material safety sheet)
Jestryl Synthesis Reference
No information avaliable
Jestryl Molecular Weight
147.196 g/mol
Jestryl Melting Point
210 oC
Jestryl H2O Solubility
1 g/ml
Jestryl State
Solid
Jestryl LogP
-3.78
Jestryl Dosage Forms
Liquid; Solution; Tablet
Jestryl Indication
Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.
Jestryl Pharmacology
Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).
Jestryl Absorption
Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.
Jestryl side effects and Toxicity
Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.
Jestryl Patient Information
No information avaliable
Jestryl Organisms Affected
Humans and other mammals
