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Jestryl Brand names, Jestryl Analogs

Jestryl Brand Names Mixture

  • No information avaliable

Jestryl Chemical_Formula

C6H15N2O2+

Jestryl RX_link

http://www.rxlist.com/cgi/generic2/carbachol.htm

Jestryl fda sheet

Jestryl FDA

Jestryl msds (material safety sheet)

Jestryl MSDS

Jestryl Synthesis Reference

No information avaliable

Jestryl Molecular Weight

147.196 g/mol

Jestryl Melting Point

210 oC

Jestryl H2O Solubility

1 g/ml

Jestryl State

Solid

Jestryl LogP

-3.78

Jestryl Dosage Forms

Liquid; Solution; Tablet

Jestryl Indication

Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.

Jestryl Pharmacology

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).

Jestryl Absorption

Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.

Jestryl side effects and Toxicity

Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.

Jestryl Patient Information

No information avaliable

Jestryl Organisms Affected

Humans and other mammals