Carbamiotin
Brand names,
Carbamiotin
Analogs
Carbamiotin
Brand Names Mixture
Carbamiotin
Chemical_Formula
C6H15N2O2+
Carbamiotin
RX_link
http://www.rxlist.com/cgi/generic2/carbachol.htm
Carbamiotin
fda sheet
Carbamiotin
msds (material safety sheet)
Carbamiotin
Synthesis Reference
No information avaliable
Carbamiotin
Molecular Weight
147.196 g/mol
Carbamiotin
Melting Point
210 oC
Carbamiotin
H2O Solubility
1 g/ml
Carbamiotin
State
Solid
Carbamiotin
LogP
-3.78
Carbamiotin
Dosage Forms
Liquid; Solution; Tablet
Carbamiotin
Indication
Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.
Carbamiotin
Pharmacology
Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).
Carbamiotin
Absorption
Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.
Carbamiotin
side effects and Toxicity
Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.
Carbamiotin
Patient Information
No information avaliable
Carbamiotin
Organisms Affected
Humans and other mammals