Lentin
Brand names,
Lentin
Analogs
Lentin
Brand Names Mixture
Lentin
Chemical_Formula
C6H15N2O2+
Lentin
RX_link
http://www.rxlist.com/cgi/generic2/carbachol.htm
Lentin
fda sheet
Lentin
msds (material safety sheet)
Lentin
Synthesis Reference
No information avaliable
Lentin
Molecular Weight
147.196 g/mol
Lentin
Melting Point
210 oC
Lentin
H2O Solubility
1 g/ml
Lentin
State
Solid
Lentin
LogP
-3.78
Lentin
Dosage Forms
Liquid; Solution; Tablet
Lentin
Indication
Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.
Lentin
Pharmacology
Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).
Lentin
Absorption
Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.
Lentin
side effects and Toxicity
Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.
Lentin
Patient Information
No information avaliable
Lentin
Organisms Affected
Humans and other mammals