Carbachol hydrochloride

Carbachol hydrochloride Brand names, Carbachol hydrochloride Analogs

Carbachol hydrochloride Brand Names Mixture

No information avaliable

Carbachol hydrochloride Chemical_Formula

C₆H₁₅N₂O₂+

Carbachol hydrochloride RX_link

http://www.rxlist.com/cgi/generic2/carbachol.htm

Carbachol hydrochloride fda sheet

Carbachol_hydrochloride FDA

Carbachol hydrochloride msds (material safety sheet)

Carbachol_hydrochloride MSDS

Carbachol hydrochloride Synthesis Reference

No information avaliable

Carbachol hydrochloride Molecular Weight

147.196 g/mol

Carbachol hydrochloride Melting Point

210 ^oC

Carbachol hydrochloride H₂O Solubility

1 g/ml

Carbachol hydrochloride State

Solid

Carbachol hydrochloride LogP

-3.78

Carbachol hydrochloride Dosage Forms

Liquid; Solution; Tablet

Carbachol hydrochloride Indication

Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.

Carbachol hydrochloride Pharmacology

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).

Carbachol hydrochloride Absorption

Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.

Carbachol hydrochloride side effects and Toxicity

Oral, mouse: LD₅₀ = 15 mg/kg; Oral, rat: LD₅₀ = 40 mg/kg.

Carbachol hydrochloride Patient Information