Carbacolina
Carbacolina Brand names, Carbacolina Analogs
- CB
- Carbachol USP27
- Carbachol chloride
- Carbachol hydrochloride
- Carbacholin
- Carbacholine
- Carbacholine chloride
- Carbacolina
- Carbaminocholine chloride
- Carbaminoylcholine chloride
- Carbamiotin
- Carbamoylcholine chloride
- Carbamoylcholine-hydrochloride
- Carbamylcholine chloride
- Carbastat
- Carbastat intraocular
- Carbochol
- Carbocholin
- Carbocholine
- Carboptic
- Carbyl
- Carcholin
- Choline carbamate chloride
- Choline chloride carbamate
- Choline chloride, carbamoyl-
- Choline chlorine carbamate
- Choline, chloride, carbamate
- Coletyl
- Doryl
- Isopto Carbachol
- Jestryl
- Karbachol
- Karbamoylcholin chlorid
- Lentin
- Lentine
- Miostat
- Mistura C
- Moryl
- P. V. Carbachol
- Rilentol
- Vasoperif
Carbacolina Brand Names Mixture
- No information avaliable
Carbacolina Chemical_Formula
C6H15N2O2+
Carbacolina RX_link
http://www.rxlist.com/cgi/generic2/carbachol.htm
Carbacolina fda sheet
Carbacolina msds (material safety sheet)
Carbacolina Synthesis Reference
No information avaliable
Carbacolina Molecular Weight
147.196 g/mol
Carbacolina Melting Point
210 oC
Carbacolina H2O Solubility
1 g/ml
Carbacolina State
Solid
Carbacolina LogP
-3.78
Carbacolina Dosage Forms
Liquid; Solution; Tablet
Carbacolina Indication
Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.
Carbacolina Pharmacology
Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).
Carbacolina Absorption
Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.
Carbacolina side effects and Toxicity
Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.
Carbacolina Patient Information
No information avaliable
Carbacolina Organisms Affected
Humans and other mammals
