Choline carbamate chloride

Choline carbamate chloride Brand names, Choline carbamate chloride Analogs

Choline carbamate chloride Brand Names Mixture

No information avaliable

Choline carbamate chloride Chemical_Formula

C₆H₁₅N₂O₂+

Choline carbamate chloride RX_link

http://www.rxlist.com/cgi/generic2/carbachol.htm

Choline carbamate chloride fda sheet

Choline_carbamate_chloride FDA

Choline carbamate chloride msds (material safety sheet)

Choline_carbamate_chloride MSDS

Choline carbamate chloride Synthesis Reference

No information avaliable

Choline carbamate chloride Molecular Weight

147.196 g/mol

Choline carbamate chloride Melting Point

210 ^oC

Choline carbamate chloride H₂O Solubility

1 g/ml

Choline carbamate chloride State

Solid

Choline carbamate chloride LogP

-3.78

Choline carbamate chloride Dosage Forms

Liquid; Solution; Tablet

Choline carbamate chloride Indication

Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.

Choline carbamate chloride Pharmacology

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).

Choline carbamate chloride Absorption

Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.

Choline carbamate chloride side effects and Toxicity

Oral, mouse: LD₅₀ = 15 mg/kg; Oral, rat: LD₅₀ = 40 mg/kg.

Choline carbamate chloride Patient Information