Moryl
Brand names,
Moryl
Analogs
Moryl
Brand Names Mixture
Moryl
Chemical_Formula
C6H15N2O2+
Moryl
RX_link
http://www.rxlist.com/cgi/generic2/carbachol.htm
Moryl
fda sheet
Moryl
msds (material safety sheet)
Moryl
Synthesis Reference
No information avaliable
Moryl
Molecular Weight
147.196 g/mol
Moryl
Melting Point
210 oC
Moryl
H2O Solubility
1 g/ml
Moryl
State
Solid
Moryl
LogP
-3.78
Moryl
Dosage Forms
Liquid; Solution; Tablet
Moryl
Indication
Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.
Moryl
Pharmacology
Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).
Moryl
Absorption
Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.
Moryl
side effects and Toxicity
Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.
Moryl
Patient Information
No information avaliable
Moryl
Organisms Affected
Humans and other mammals