Carbocholin
Carbocholin Brand names, Carbocholin Analogs
- CB
- Carbachol USP27
- Carbachol chloride
- Carbachol hydrochloride
- Carbacholin
- Carbacholine
- Carbacholine chloride
- Carbacolina
- Carbaminocholine chloride
- Carbaminoylcholine chloride
- Carbamiotin
- Carbamoylcholine chloride
- Carbamoylcholine-hydrochloride
- Carbamylcholine chloride
- Carbastat
- Carbastat intraocular
- Carbochol
- Carbocholin
- Carbocholine
- Carboptic
- Carbyl
- Carcholin
- Choline carbamate chloride
- Choline chloride carbamate
- Choline chloride, carbamoyl-
- Choline chlorine carbamate
- Choline, chloride, carbamate
- Coletyl
- Doryl
- Isopto Carbachol
- Jestryl
- Karbachol
- Karbamoylcholin chlorid
- Lentin
- Lentine
- Miostat
- Mistura C
- Moryl
- P. V. Carbachol
- Rilentol
- Vasoperif
Carbocholin Brand Names Mixture
- No information avaliable
Carbocholin Chemical_Formula
C6H15N2O2+
Carbocholin RX_link
http://www.rxlist.com/cgi/generic2/carbachol.htm
Carbocholin fda sheet
Carbocholin msds (material safety sheet)
Carbocholin Synthesis Reference
No information avaliable
Carbocholin Molecular Weight
147.196 g/mol
Carbocholin Melting Point
210 oC
Carbocholin H2O Solubility
1 g/ml
Carbocholin State
Solid
Carbocholin LogP
-3.78
Carbocholin Dosage Forms
Liquid; Solution; Tablet
Carbocholin Indication
Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.
Carbocholin Pharmacology
Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).
Carbocholin Absorption
Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.
Carbocholin side effects and Toxicity
Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.
Carbocholin Patient Information
No information avaliable
Carbocholin Organisms Affected
Humans and other mammals
