Carbamoylcholine chloride
Brand names,
Carbamoylcholine chloride
Analogs
Carbamoylcholine chloride
Brand Names Mixture
Carbamoylcholine chloride
Chemical_Formula
C6H15N2O2+
Carbamoylcholine chloride
RX_link
http://www.rxlist.com/cgi/generic2/carbachol.htm
Carbamoylcholine chloride
fda sheet
Carbamoylcholine chloride
msds (material safety sheet)
Carbamoylcholine chloride
Synthesis Reference
No information avaliable
Carbamoylcholine chloride
Molecular Weight
147.196 g/mol
Carbamoylcholine chloride
Melting Point
210 oC
Carbamoylcholine chloride
H2O Solubility
1 g/ml
Carbamoylcholine chloride
State
Solid
Carbamoylcholine chloride
LogP
-3.78
Carbamoylcholine chloride
Dosage Forms
Liquid; Solution; Tablet
Carbamoylcholine chloride
Indication
Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.
Carbamoylcholine chloride
Pharmacology
Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).
Carbamoylcholine chloride
Absorption
Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.
Carbamoylcholine chloride
side effects and Toxicity
Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.
Carbamoylcholine chloride
Patient Information
No information avaliable
Carbamoylcholine chloride
Organisms Affected
Humans and other mammals