Carbocholine en es it fr

Carbocholine Brand names, Carbocholine Analogs

Carbocholine Brand Names Mixture

  • No information avaliable

Carbocholine Chemical_Formula

C6H15N2O2+

Carbocholine RX_link

http://www.rxlist.com/cgi/generic2/carbachol.htm

Carbocholine fda sheet

Carbocholine FDA

Carbocholine msds (material safety sheet)

Carbocholine MSDS

Carbocholine Synthesis Reference

No information avaliable

Carbocholine Molecular Weight

147.196 g/mol

Carbocholine Melting Point

210 oC

Carbocholine H2O Solubility

1 g/ml

Carbocholine State

Solid

Carbocholine LogP

-3.78

Carbocholine Dosage Forms

Liquid; Solution; Tablet

Carbocholine Indication

Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.

Carbocholine Pharmacology

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).

Carbocholine Absorption

Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.

Carbocholine side effects and Toxicity

Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.

Carbocholine Patient Information

No information avaliable

Carbocholine Organisms Affected

Humans and other mammals