Carbaminocholine chloride

Carbaminocholine chloride Brand names, Carbaminocholine chloride Analogs

Carbaminocholine chloride Brand Names Mixture

No information avaliable

Carbaminocholine chloride Chemical_Formula

C₆H₁₅N₂O₂+

Carbaminocholine chloride RX_link

http://www.rxlist.com/cgi/generic2/carbachol.htm

Carbaminocholine chloride fda sheet

Carbaminocholine_chloride FDA

Carbaminocholine chloride msds (material safety sheet)

Carbaminocholine_chloride MSDS

Carbaminocholine chloride Synthesis Reference

No information avaliable

Carbaminocholine chloride Molecular Weight

147.196 g/mol

Carbaminocholine chloride Melting Point

210 ^oC

Carbaminocholine chloride H₂O Solubility

1 g/ml

Carbaminocholine chloride State

Solid

Carbaminocholine chloride LogP

-3.78

Carbaminocholine chloride Dosage Forms

Liquid; Solution; Tablet

Carbaminocholine chloride Indication

Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.

Carbaminocholine chloride Pharmacology

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).

Carbaminocholine chloride Absorption

Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.

Carbaminocholine chloride side effects and Toxicity

Oral, mouse: LD₅₀ = 15 mg/kg; Oral, rat: LD₅₀ = 40 mg/kg.

Carbaminocholine chloride Patient Information