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Carbochol Brand names, Carbochol Analogs

Carbochol Brand Names Mixture

  • No information avaliable

Carbochol Chemical_Formula

C6H15N2O2+

Carbochol RX_link

http://www.rxlist.com/cgi/generic2/carbachol.htm

Carbochol fda sheet

Carbochol FDA

Carbochol msds (material safety sheet)

Carbochol MSDS

Carbochol Synthesis Reference

No information avaliable

Carbochol Molecular Weight

147.196 g/mol

Carbochol Melting Point

210 oC

Carbochol H2O Solubility

1 g/ml

Carbochol State

Solid

Carbochol LogP

-3.78

Carbochol Dosage Forms

Liquid; Solution; Tablet

Carbochol Indication

Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.

Carbochol Pharmacology

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).

Carbochol Absorption

Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.

Carbochol side effects and Toxicity

Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.

Carbochol Patient Information

No information avaliable

Carbochol Organisms Affected

Humans and other mammals