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Doryl Brand names, Doryl Analogs

Doryl Brand Names Mixture

  • No information avaliable

Doryl Chemical_Formula

C6H15N2O2+

Doryl RX_link

http://www.rxlist.com/cgi/generic2/carbachol.htm

Doryl fda sheet

Doryl FDA

Doryl msds (material safety sheet)

Doryl MSDS

Doryl Synthesis Reference

No information avaliable

Doryl Molecular Weight

147.196 g/mol

Doryl Melting Point

210 oC

Doryl H2O Solubility

1 g/ml

Doryl State

Solid

Doryl LogP

-3.78

Doryl Dosage Forms

Liquid; Solution; Tablet

Doryl Indication

Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.

Doryl Pharmacology

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).

Doryl Absorption

Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.

Doryl side effects and Toxicity

Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.

Doryl Patient Information

No information avaliable

Doryl Organisms Affected

Humans and other mammals