Doryl
Doryl Brand names, Doryl Analogs
- CB
- Carbachol USP27
- Carbachol chloride
- Carbachol hydrochloride
- Carbacholin
- Carbacholine
- Carbacholine chloride
- Carbacolina
- Carbaminocholine chloride
- Carbaminoylcholine chloride
- Carbamiotin
- Carbamoylcholine chloride
- Carbamoylcholine-hydrochloride
- Carbamylcholine chloride
- Carbastat
- Carbastat intraocular
- Carbochol
- Carbocholin
- Carbocholine
- Carboptic
- Carbyl
- Carcholin
- Choline carbamate chloride
- Choline chloride carbamate
- Choline chloride, carbamoyl-
- Choline chlorine carbamate
- Choline, chloride, carbamate
- Coletyl
- Doryl
- Isopto Carbachol
- Jestryl
- Karbachol
- Karbamoylcholin chlorid
- Lentin
- Lentine
- Miostat
- Mistura C
- Moryl
- P. V. Carbachol
- Rilentol
- Vasoperif
Doryl Brand Names Mixture
- No information avaliable
Doryl Chemical_Formula
C6H15N2O2+
Doryl RX_link
http://www.rxlist.com/cgi/generic2/carbachol.htm
Doryl fda sheet
Doryl msds (material safety sheet)
Doryl Synthesis Reference
No information avaliable
Doryl Molecular Weight
147.196 g/mol
Doryl Melting Point
210 oC
Doryl H2O Solubility
1 g/ml
Doryl State
Solid
Doryl LogP
-3.78
Doryl Dosage Forms
Liquid; Solution; Tablet
Doryl Indication
Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.
Doryl Pharmacology
Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).
Doryl Absorption
Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.
Doryl side effects and Toxicity
Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.
Doryl Patient Information
No information avaliable
Doryl Organisms Affected
Humans and other mammals
