Carbastat

Carbastat Brand names, Carbastat Analogs

Carbastat Brand Names Mixture

No information avaliable

Carbastat Chemical_Formula

C₆H₁₅N₂O₂+

Carbastat RX_link

http://www.rxlist.com/cgi/generic2/carbachol.htm

Carbastat fda sheet

Carbastat FDA

Carbastat msds (material safety sheet)

Carbastat MSDS

Carbastat Synthesis Reference

No information avaliable

Carbastat Molecular Weight

147.196 g/mol

Carbastat Melting Point

210 ^oC

Carbastat H₂O Solubility

1 g/ml

Carbastat State

Solid

Carbastat LogP

-3.78

Carbastat Dosage Forms

Liquid; Solution; Tablet

Carbastat Indication

Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.

Carbastat Pharmacology

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).

Carbastat Absorption

Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.

Carbastat side effects and Toxicity

Oral, mouse: LD₅₀ = 15 mg/kg; Oral, rat: LD₅₀ = 40 mg/kg.

Carbastat Patient Information