Karbachol
Karbachol Brand names, Karbachol Analogs
- CB
- Carbachol USP27
- Carbachol chloride
- Carbachol hydrochloride
- Carbacholin
- Carbacholine
- Carbacholine chloride
- Carbacolina
- Carbaminocholine chloride
- Carbaminoylcholine chloride
- Carbamiotin
- Carbamoylcholine chloride
- Carbamoylcholine-hydrochloride
- Carbamylcholine chloride
- Carbastat
- Carbastat intraocular
- Carbochol
- Carbocholin
- Carbocholine
- Carboptic
- Carbyl
- Carcholin
- Choline carbamate chloride
- Choline chloride carbamate
- Choline chloride, carbamoyl-
- Choline chlorine carbamate
- Choline, chloride, carbamate
- Coletyl
- Doryl
- Isopto Carbachol
- Jestryl
- Karbachol
- Karbamoylcholin chlorid
- Lentin
- Lentine
- Miostat
- Mistura C
- Moryl
- P. V. Carbachol
- Rilentol
- Vasoperif
Karbachol Brand Names Mixture
- No information avaliable
Karbachol Chemical_Formula
C6H15N2O2+
Karbachol RX_link
http://www.rxlist.com/cgi/generic2/carbachol.htm
Karbachol fda sheet
Karbachol msds (material safety sheet)
Karbachol Synthesis Reference
No information avaliable
Karbachol Molecular Weight
147.196 g/mol
Karbachol Melting Point
210 oC
Karbachol H2O Solubility
1 g/ml
Karbachol State
Solid
Karbachol LogP
-3.78
Karbachol Dosage Forms
Liquid; Solution; Tablet
Karbachol Indication
Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.
Karbachol Pharmacology
Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).
Karbachol Absorption
Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.
Karbachol side effects and Toxicity
Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.
Karbachol Patient Information
No information avaliable
Karbachol Organisms Affected
Humans and other mammals
