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Karbachol Brand names, Karbachol Analogs

Karbachol Brand Names Mixture

  • No information avaliable

Karbachol Chemical_Formula


Karbachol RX_link


Karbachol fda sheet

Karbachol FDA

Karbachol msds (material safety sheet)

Karbachol MSDS

Karbachol Synthesis Reference

No information avaliable

Karbachol Molecular Weight

147.196 g/mol

Karbachol Melting Point

210 oC

Karbachol H2O Solubility

1 g/ml

Karbachol State


Karbachol LogP


Karbachol Dosage Forms

Liquid; Solution; Tablet

Karbachol Indication

Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.

Karbachol Pharmacology

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).

Karbachol Absorption

Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.

Karbachol side effects and Toxicity

Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.

Karbachol Patient Information

No information avaliable

Karbachol Organisms Affected

Humans and other mammals