Choline chloride, carbamoyl-

Choline chloride, carbamoyl- Brand names, Choline chloride, carbamoyl- Analogs

Choline chloride, carbamoyl- Brand Names Mixture

No information avaliable

Choline chloride, carbamoyl- Chemical_Formula

C₆H₁₅N₂O₂+

Choline chloride, carbamoyl- RX_link

http://www.rxlist.com/cgi/generic2/carbachol.htm

Choline chloride, carbamoyl- fda sheet

Choline_chloride,_carbamoyl- FDA

Choline chloride, carbamoyl- msds (material safety sheet)

Choline_chloride,_carbamoyl- MSDS

Choline chloride, carbamoyl- Synthesis Reference

No information avaliable

Choline chloride, carbamoyl- Molecular Weight

147.196 g/mol

Choline chloride, carbamoyl- Melting Point

210 ^oC

Choline chloride, carbamoyl- H₂O Solubility

1 g/ml

Choline chloride, carbamoyl- State

Solid

Choline chloride, carbamoyl- LogP

-3.78

Choline chloride, carbamoyl- Dosage Forms

Liquid; Solution; Tablet

Choline chloride, carbamoyl- Indication

Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.

Choline chloride, carbamoyl- Pharmacology

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).

Choline chloride, carbamoyl- Absorption

Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.

Choline chloride, carbamoyl- side effects and Toxicity

Oral, mouse: LD₅₀ = 15 mg/kg; Oral, rat: LD₅₀ = 40 mg/kg.

Choline chloride, carbamoyl- Patient Information