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Carbacholine Brand names, Carbacholine Analogs

Carbacholine Brand Names Mixture

  • No information avaliable

Carbacholine Chemical_Formula

C6H15N2O2+

Carbacholine RX_link

http://www.rxlist.com/cgi/generic2/carbachol.htm

Carbacholine fda sheet

Carbacholine FDA

Carbacholine msds (material safety sheet)

Carbacholine MSDS

Carbacholine Synthesis Reference

No information avaliable

Carbacholine Molecular Weight

147.196 g/mol

Carbacholine Melting Point

210 oC

Carbacholine H2O Solubility

1 g/ml

Carbacholine State

Solid

Carbacholine LogP

-3.78

Carbacholine Dosage Forms

Liquid; Solution; Tablet

Carbacholine Indication

Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.

Carbacholine Pharmacology

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).

Carbacholine Absorption

Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.

Carbacholine side effects and Toxicity

Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.

Carbacholine Patient Information

No information avaliable

Carbacholine Organisms Affected

Humans and other mammals