Carbacholine
Carbacholine Brand names, Carbacholine Analogs
- CB
- Carbachol USP27
- Carbachol chloride
- Carbachol hydrochloride
- Carbacholin
- Carbacholine
- Carbacholine chloride
- Carbacolina
- Carbaminocholine chloride
- Carbaminoylcholine chloride
- Carbamiotin
- Carbamoylcholine chloride
- Carbamoylcholine-hydrochloride
- Carbamylcholine chloride
- Carbastat
- Carbastat intraocular
- Carbochol
- Carbocholin
- Carbocholine
- Carboptic
- Carbyl
- Carcholin
- Choline carbamate chloride
- Choline chloride carbamate
- Choline chloride, carbamoyl-
- Choline chlorine carbamate
- Choline, chloride, carbamate
- Coletyl
- Doryl
- Isopto Carbachol
- Jestryl
- Karbachol
- Karbamoylcholin chlorid
- Lentin
- Lentine
- Miostat
- Mistura C
- Moryl
- P. V. Carbachol
- Rilentol
- Vasoperif
Carbacholine Brand Names Mixture
- No information avaliable
Carbacholine Chemical_Formula
C6H15N2O2+
Carbacholine RX_link
http://www.rxlist.com/cgi/generic2/carbachol.htm
Carbacholine fda sheet
Carbacholine msds (material safety sheet)
Carbacholine Synthesis Reference
No information avaliable
Carbacholine Molecular Weight
147.196 g/mol
Carbacholine Melting Point
210 oC
Carbacholine H2O Solubility
1 g/ml
Carbacholine State
Solid
Carbacholine LogP
-3.78
Carbacholine Dosage Forms
Liquid; Solution; Tablet
Carbacholine Indication
Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.
Carbacholine Pharmacology
Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).
Carbacholine Absorption
Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.
Carbacholine side effects and Toxicity
Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.
Carbacholine Patient Information
No information avaliable
Carbacholine Organisms Affected
Humans and other mammals
