Carbacholine chloride

Carbacholine chloride Brand names, Carbacholine chloride Analogs

Carbacholine chloride Brand Names Mixture

No information avaliable

Carbacholine chloride Chemical_Formula

C₆H₁₅N₂O₂+

Carbacholine chloride RX_link

http://www.rxlist.com/cgi/generic2/carbachol.htm

Carbacholine chloride fda sheet

Carbacholine_chloride FDA

Carbacholine chloride msds (material safety sheet)

Carbacholine_chloride MSDS

Carbacholine chloride Synthesis Reference

No information avaliable

Carbacholine chloride Molecular Weight

147.196 g/mol

Carbacholine chloride Melting Point

210 ^oC

Carbacholine chloride H₂O Solubility

1 g/ml

Carbacholine chloride State

Solid

Carbacholine chloride LogP

-3.78

Carbacholine chloride Dosage Forms

Liquid; Solution; Tablet

Carbacholine chloride Indication

Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.

Carbacholine chloride Pharmacology

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).

Carbacholine chloride Absorption

Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.

Carbacholine chloride side effects and Toxicity

Oral, mouse: LD₅₀ = 15 mg/kg; Oral, rat: LD₅₀ = 40 mg/kg.

Carbacholine chloride Patient Information