Carbaminoylcholine chloride
Brand names,
Carbaminoylcholine chloride
Analogs
Carbaminoylcholine chloride
Brand Names Mixture
Carbaminoylcholine chloride
Chemical_Formula
C6H15N2O2+
Carbaminoylcholine chloride
RX_link
http://www.rxlist.com/cgi/generic2/carbachol.htm
Carbaminoylcholine chloride
fda sheet
Carbaminoylcholine chloride
msds (material safety sheet)
Carbaminoylcholine chloride
Synthesis Reference
No information avaliable
Carbaminoylcholine chloride
Molecular Weight
147.196 g/mol
Carbaminoylcholine chloride
Melting Point
210 oC
Carbaminoylcholine chloride
H2O Solubility
1 g/ml
Carbaminoylcholine chloride
State
Solid
Carbaminoylcholine chloride
LogP
-3.78
Carbaminoylcholine chloride
Dosage Forms
Liquid; Solution; Tablet
Carbaminoylcholine chloride
Indication
Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.
Carbaminoylcholine chloride
Pharmacology
Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).
Carbaminoylcholine chloride
Absorption
Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.
Carbaminoylcholine chloride
side effects and Toxicity
Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.
Carbaminoylcholine chloride
Patient Information
No information avaliable
Carbaminoylcholine chloride
Organisms Affected
Humans and other mammals