Carbachol USP27

Carbachol USP27 Brand names, Carbachol USP27 Analogs

Carbachol USP27 Brand Names Mixture

No information avaliable

Carbachol USP27 Chemical_Formula

C₆H₁₅N₂O₂+

Carbachol USP27 RX_link

http://www.rxlist.com/cgi/generic2/carbachol.htm

Carbachol USP27 fda sheet

Carbachol_USP27 FDA

Carbachol USP27 msds (material safety sheet)

Carbachol_USP27 MSDS

Carbachol USP27 Synthesis Reference

No information avaliable

Carbachol USP27 Molecular Weight

147.196 g/mol

Carbachol USP27 Melting Point

210 ^oC

Carbachol USP27 H₂O Solubility

1 g/ml

Carbachol USP27 State

Solid

Carbachol USP27 LogP

-3.78

Carbachol USP27 Dosage Forms

Liquid; Solution; Tablet

Carbachol USP27 Indication

Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.

Carbachol USP27 Pharmacology

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).

Carbachol USP27 Absorption

Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.

Carbachol USP27 side effects and Toxicity

Oral, mouse: LD₅₀ = 15 mg/kg; Oral, rat: LD₅₀ = 40 mg/kg.

Carbachol USP27 Patient Information