Choline chloride carbamate

Choline chloride carbamate Brand names, Choline chloride carbamate Analogs

Choline chloride carbamate Brand Names Mixture

No information avaliable

Choline chloride carbamate Chemical_Formula

C₆H₁₅N₂O₂+

Choline chloride carbamate RX_link

http://www.rxlist.com/cgi/generic2/carbachol.htm

Choline chloride carbamate fda sheet

Choline_chloride_carbamate FDA

Choline chloride carbamate msds (material safety sheet)

Choline_chloride_carbamate MSDS

Choline chloride carbamate Synthesis Reference

No information avaliable

Choline chloride carbamate Molecular Weight

147.196 g/mol

Choline chloride carbamate Melting Point

210 ^oC

Choline chloride carbamate H₂O Solubility

1 g/ml

Choline chloride carbamate State

Solid

Choline chloride carbamate LogP

-3.78

Choline chloride carbamate Dosage Forms

Liquid; Solution; Tablet

Choline chloride carbamate Indication

Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.

Choline chloride carbamate Pharmacology

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).

Choline chloride carbamate Absorption

Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.

Choline chloride carbamate side effects and Toxicity

Oral, mouse: LD₅₀ = 15 mg/kg; Oral, rat: LD₅₀ = 40 mg/kg.

Choline chloride carbamate Patient Information