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Lentine Brand names, Lentine Analogs

Lentine Brand Names Mixture

  • No information avaliable

Lentine Chemical_Formula

C6H15N2O2+

Lentine RX_link

http://www.rxlist.com/cgi/generic2/carbachol.htm

Lentine fda sheet

Lentine FDA

Lentine msds (material safety sheet)

Lentine MSDS

Lentine Synthesis Reference

No information avaliable

Lentine Molecular Weight

147.196 g/mol

Lentine Melting Point

210 oC

Lentine H2O Solubility

1 g/ml

Lentine State

Solid

Lentine LogP

-3.78

Lentine Dosage Forms

Liquid; Solution; Tablet

Lentine Indication

Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.

Lentine Pharmacology

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).

Lentine Absorption

Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.

Lentine side effects and Toxicity

Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.

Lentine Patient Information

No information avaliable

Lentine Organisms Affected

Humans and other mammals