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Carbacholin Brand names, Carbacholin Analogs

Carbacholin Brand Names Mixture

  • No information avaliable

Carbacholin Chemical_Formula

C6H15N2O2+

Carbacholin RX_link

http://www.rxlist.com/cgi/generic2/carbachol.htm

Carbacholin fda sheet

Carbacholin FDA

Carbacholin msds (material safety sheet)

Carbacholin MSDS

Carbacholin Synthesis Reference

No information avaliable

Carbacholin Molecular Weight

147.196 g/mol

Carbacholin Melting Point

210 oC

Carbacholin H2O Solubility

1 g/ml

Carbacholin State

Solid

Carbacholin LogP

-3.78

Carbacholin Dosage Forms

Liquid; Solution; Tablet

Carbacholin Indication

Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.

Carbacholin Pharmacology

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).

Carbacholin Absorption

Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.

Carbacholin side effects and Toxicity

Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.

Carbacholin Patient Information

No information avaliable

Carbacholin Organisms Affected

Humans and other mammals