Carcholin

Carcholin Brand names, Carcholin Analogs

Carcholin Brand Names Mixture

No information avaliable

Carcholin Chemical_Formula

C₆H₁₅N₂O₂+

Carcholin RX_link

http://www.rxlist.com/cgi/generic2/carbachol.htm

Carcholin fda sheet

Carcholin FDA

Carcholin msds (material safety sheet)

Carcholin MSDS

Carcholin Synthesis Reference

No information avaliable

Carcholin Molecular Weight

147.196 g/mol

Carcholin Melting Point

210 ^oC

Carcholin H₂O Solubility

1 g/ml

Carcholin State

Solid

Carcholin LogP

-3.78

Carcholin Dosage Forms

Liquid; Solution; Tablet

Carcholin Indication

Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.

Carcholin Pharmacology

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).

Carcholin Absorption

Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.

Carcholin side effects and Toxicity

Oral, mouse: LD₅₀ = 15 mg/kg; Oral, rat: LD₅₀ = 40 mg/kg.

Carcholin Patient Information