Mistura C
Brand names,
Mistura C
Analogs
Mistura C
Brand Names Mixture
Mistura C
Chemical_Formula
C6H15N2O2+
Mistura C
RX_link
http://www.rxlist.com/cgi/generic2/carbachol.htm
Mistura C
fda sheet
Mistura C
msds (material safety sheet)
Mistura C
Synthesis Reference
No information avaliable
Mistura C
Molecular Weight
147.196 g/mol
Mistura C
Melting Point
210 oC
Mistura C
H2O Solubility
1 g/ml
Mistura C
State
Solid
Mistura C
LogP
-3.78
Mistura C
Dosage Forms
Liquid; Solution; Tablet
Mistura C
Indication
Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.
Mistura C
Pharmacology
Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).
Mistura C
Absorption
Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.
Mistura C
side effects and Toxicity
Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.
Mistura C
Patient Information
No information avaliable
Mistura C
Organisms Affected
Humans and other mammals