Rilentol
Brand names,
Rilentol
Analogs
Rilentol
Brand Names Mixture
Rilentol
Chemical_Formula
C6H15N2O2+
Rilentol
RX_link
http://www.rxlist.com/cgi/generic2/carbachol.htm
Rilentol
fda sheet
Rilentol
msds (material safety sheet)
Rilentol
Synthesis Reference
No information avaliable
Rilentol
Molecular Weight
147.196 g/mol
Rilentol
Melting Point
210 oC
Rilentol
H2O Solubility
1 g/ml
Rilentol
State
Solid
Rilentol
LogP
-3.78
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Dosage Forms
Liquid; Solution; Tablet
Rilentol
Indication
Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.
Rilentol
Pharmacology
Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).
Rilentol
Absorption
Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.
Rilentol
side effects and Toxicity
Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.
Rilentol
Patient Information
No information avaliable
Rilentol
Organisms Affected
Humans and other mammals