Choline, chloride, carbamate

Choline, chloride, carbamate Brand names, Choline, chloride, carbamate Analogs

Choline, chloride, carbamate Brand Names Mixture

No information avaliable

Choline, chloride, carbamate Chemical_Formula

C₆H₁₅N₂O₂+

Choline, chloride, carbamate RX_link

http://www.rxlist.com/cgi/generic2/carbachol.htm

Choline, chloride, carbamate fda sheet

Choline,_chloride,_carbamate FDA

Choline, chloride, carbamate msds (material safety sheet)

Choline,_chloride,_carbamate MSDS

Choline, chloride, carbamate Synthesis Reference

No information avaliable

Choline, chloride, carbamate Molecular Weight

147.196 g/mol

Choline, chloride, carbamate Melting Point

210 ^oC

Choline, chloride, carbamate H₂O Solubility

1 g/ml

Choline, chloride, carbamate State

Solid

Choline, chloride, carbamate LogP

-3.78

Choline, chloride, carbamate Dosage Forms

Liquid; Solution; Tablet

Choline, chloride, carbamate Indication

Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.

Choline, chloride, carbamate Pharmacology

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).

Choline, chloride, carbamate Absorption

Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.

Choline, chloride, carbamate side effects and Toxicity

Oral, mouse: LD₅₀ = 15 mg/kg; Oral, rat: LD₅₀ = 40 mg/kg.

Choline, chloride, carbamate Patient Information