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Carbachol Brand names, Carbachol Analogs

Carbachol Brand Names Mixture

  • No information avaliable

Carbachol Chemical_Formula

C6H15N2O2+

Carbachol RX_link

http://www.rxlist.com/cgi/generic2/carbachol.htm

Carbachol fda sheet

Carbachol FDA

Carbachol msds (material safety sheet)

Carbachol MSDS

Carbachol Synthesis Reference

No information avaliable

Carbachol Molecular Weight

147.196 g/mol

Carbachol Melting Point

210 oC

Carbachol H2O Solubility

1 g/ml

Carbachol State

Solid

Carbachol LogP

-3.78

Carbachol Dosage Forms

Liquid; Solution; Tablet

Carbachol Indication

Primarily used in the treatment of glaucoma, but is also used during ophthalmic surgery.

Carbachol Pharmacology

Carbachol is a potent cholinergic (parasympathomimetic) agent which produces constriction of the iris and ciliary body resulting in reduction in intraocular pressure. The exact mechanism by which carbachol lowers intraocular pressure is not precisely known. In the cat and rat, carbachol is well-known for its ability to induce rapid eye movement (REM) sleep when microinjected into the pontine reticular formation. Carbachol elicits this REM sleep-like state via activation of postsynaptic muscarinic cholinergic receptors (mAChRs).

Carbachol Absorption

Not well absorbed in the gastro-intestinal tract, and does not cross the blood-brain barrier.

Carbachol side effects and Toxicity

Oral, mouse: LD50 = 15 mg/kg; Oral, rat: LD50 = 40 mg/kg.

Carbachol Patient Information

No information avaliable

Carbachol Organisms Affected

Humans and other mammals