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Bioguard Brand names, Bioguard Analogs

Bioguard Brand Names Mixture

  • No information avaliable

Bioguard Chemical_Formula


Bioguard RX_link

Bioguard fda sheet

Bioguard msds (material safety sheet)

Bioguard Synthesis Reference

No information avaliable

Bioguard Molecular Weight

192.258 g/mol

Bioguard Melting Point

246-266 oC

Bioguard H2O Solubility

1.07E+004 mg/L

Bioguard State


Bioguard LogP


Bioguard Dosage Forms

400 mg and 600 mg tablets for oral administration

Bioguard Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Bioguard Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Bioguard Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Bioguard side effects and Toxicity

The oral LD50 of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Bioguard Patient Information

Bioguard Organisms Affected

Humans and other mammals