PharmacyCodes



Mertect 340f en es it fr

Mertect 340f Brand names, Mertect 340f Analogs

Mertect 340f Brand Names Mixture

  • No information avaliable

Mertect 340f Chemical_Formula

C11H16N2O

Mertect 340f RX_link

http://www.rxlist.com/cgi/generic3/tocainide.htm

Mertect 340f fda sheet

Mertect 340f msds (material safety sheet)

Mertect 340f Synthesis Reference

No information avaliable

Mertect 340f Molecular Weight

192.258 g/mol

Mertect 340f Melting Point

246-266 oC

Mertect 340f H2O Solubility

1.07E+004 mg/L

Mertect 340f State

Solid

Mertect 340f LogP

1.308

Mertect 340f Dosage Forms

400 mg and 600 mg tablets for oral administration

Mertect 340f Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Mertect 340f Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Mertect 340f Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Mertect 340f side effects and Toxicity

The oral LD50 of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Mertect 340f Patient Information

Mertect 340f Organisms Affected

Humans and other mammals