Mycozol

Mycozol Brand names, Mycozol Analogs

Mycozol Brand Names Mixture

No information avaliable

Mycozol Chemical_Formula

C₁₁H₁₆N₂O

Mycozol RX_link

http://www.rxlist.com/cgi/generic3/tocainide.htm

Mycozol fda sheet

Mycozol msds (material safety sheet)

Mycozol Synthesis Reference

No information avaliable

Mycozol Molecular Weight

192.258 g/mol

Mycozol Melting Point

246-266 ^oC

Mycozol H₂O Solubility

1.07E+004 mg/L

Mycozol State

Solid

Mycozol LogP

1.308

Mycozol Dosage Forms

400 mg and 600 mg tablets for oral administration

Mycozol Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Mycozol Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Mycozol Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Mycozol side effects and Toxicity

The oral LD₅₀ of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Mycozol Patient Information

Mycozol Organisms Affected

Humans and other mammals