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Mertect Brand names, Mertect Analogs

Mertect Brand Names Mixture

  • No information avaliable

Mertect Chemical_Formula


Mertect RX_link

Mertect fda sheet

Mertect msds (material safety sheet)

Mertect Synthesis Reference

No information avaliable

Mertect Molecular Weight

192.258 g/mol

Mertect Melting Point

246-266 oC

Mertect H2O Solubility

1.07E+004 mg/L

Mertect State


Mertect LogP


Mertect Dosage Forms

400 mg and 600 mg tablets for oral administration

Mertect Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Mertect Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Mertect Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Mertect side effects and Toxicity

The oral LD50 of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Mertect Patient Information

Mertect Organisms Affected

Humans and other mammals