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Arbotect Brand names, Arbotect Analogs

Arbotect Brand Names Mixture

  • No information avaliable

Arbotect Chemical_Formula


Arbotect RX_link

Arbotect fda sheet

Arbotect msds (material safety sheet)

Arbotect Synthesis Reference

No information avaliable

Arbotect Molecular Weight

192.258 g/mol

Arbotect Melting Point

246-266 oC

Arbotect H2O Solubility

1.07E+004 mg/L

Arbotect State


Arbotect LogP


Arbotect Dosage Forms

400 mg and 600 mg tablets for oral administration

Arbotect Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Arbotect Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Arbotect Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Arbotect side effects and Toxicity

The oral LD50 of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Arbotect Patient Information

Arbotect Organisms Affected

Humans and other mammals