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Thiabendazol Brand names, Thiabendazol Analogs

Thiabendazol Brand Names Mixture

  • No information avaliable

Thiabendazol Chemical_Formula


Thiabendazol RX_link

Thiabendazol fda sheet

Thiabendazol msds (material safety sheet)

Thiabendazol Synthesis Reference

No information avaliable

Thiabendazol Molecular Weight

192.258 g/mol

Thiabendazol Melting Point

246-266 oC

Thiabendazol H2O Solubility

1.07E+004 mg/L

Thiabendazol State


Thiabendazol LogP


Thiabendazol Dosage Forms

400 mg and 600 mg tablets for oral administration

Thiabendazol Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Thiabendazol Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Thiabendazol Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Thiabendazol side effects and Toxicity

The oral LD50 of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Thiabendazol Patient Information

Thiabendazol Organisms Affected

Humans and other mammals