Cropasal en es it fr

Cropasal Brand names, Cropasal Analogs

Cropasal Brand Names Mixture

  • No information avaliable

Cropasal Chemical_Formula


Cropasal RX_link

Cropasal fda sheet

Cropasal msds (material safety sheet)

Cropasal Synthesis Reference

No information avaliable

Cropasal Molecular Weight

192.258 g/mol

Cropasal Melting Point

246-266 oC

Cropasal H2O Solubility

1.07E+004 mg/L

Cropasal State


Cropasal LogP


Cropasal Dosage Forms

400 mg and 600 mg tablets for oral administration

Cropasal Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Cropasal Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Cropasal Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Cropasal side effects and Toxicity

The oral LD50 of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Cropasal Patient Information

Cropasal Organisms Affected

Humans and other mammals