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Tecto rph Brand names, Tecto rph Analogs

Tecto rph Brand Names Mixture

  • No information avaliable

Tecto rph Chemical_Formula


Tecto rph RX_link


Tecto rph fda sheet

Tecto rph msds (material safety sheet)

Tecto rph Synthesis Reference

No information avaliable

Tecto rph Molecular Weight

192.258 g/mol

Tecto rph Melting Point

246-266 oC

Tecto rph H2O Solubility

1.07E+004 mg/L

Tecto rph State


Tecto rph LogP


Tecto rph Dosage Forms

400 mg and 600 mg tablets for oral administration

Tecto rph Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Tecto rph Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Tecto rph Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Tecto rph side effects and Toxicity

The oral LD50 of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Tecto rph Patient Information

Tecto rph Organisms Affected

Humans and other mammals