Bovizole en es it fr

Bovizole Brand names, Bovizole Analogs

Bovizole Brand Names Mixture

  • No information avaliable

Bovizole Chemical_Formula


Bovizole RX_link

Bovizole fda sheet

Bovizole msds (material safety sheet)

Bovizole Synthesis Reference

No information avaliable

Bovizole Molecular Weight

192.258 g/mol

Bovizole Melting Point

246-266 oC

Bovizole H2O Solubility

1.07E+004 mg/L

Bovizole State


Bovizole LogP


Bovizole Dosage Forms

400 mg and 600 mg tablets for oral administration

Bovizole Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Bovizole Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Bovizole Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Bovizole side effects and Toxicity

The oral LD50 of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Bovizole Patient Information

Bovizole Organisms Affected

Humans and other mammals