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Minzolum Brand names, Minzolum Analogs

Minzolum Brand Names Mixture

  • No information avaliable

Minzolum Chemical_Formula


Minzolum RX_link


Minzolum fda sheet

Minzolum msds (material safety sheet)

Minzolum Synthesis Reference

No information avaliable

Minzolum Molecular Weight

192.258 g/mol

Minzolum Melting Point

246-266 oC

Minzolum H2O Solubility

1.07E+004 mg/L

Minzolum State


Minzolum LogP


Minzolum Dosage Forms

400 mg and 600 mg tablets for oral administration

Minzolum Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Minzolum Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Minzolum Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Minzolum side effects and Toxicity

The oral LD50 of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Minzolum Patient Information

Minzolum Organisms Affected

Humans and other mammals