Nemapan en es it fr

Nemapan Brand names, Nemapan Analogs

Nemapan Brand Names Mixture

  • No information avaliable

Nemapan Chemical_Formula


Nemapan RX_link

Nemapan fda sheet

Nemapan msds (material safety sheet)

Nemapan Synthesis Reference

No information avaliable

Nemapan Molecular Weight

192.258 g/mol

Nemapan Melting Point

246-266 oC

Nemapan H2O Solubility

1.07E+004 mg/L

Nemapan State


Nemapan LogP


Nemapan Dosage Forms

400 mg and 600 mg tablets for oral administration

Nemapan Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Nemapan Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Nemapan Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Nemapan side effects and Toxicity

The oral LD50 of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Nemapan Patient Information

Nemapan Organisms Affected

Humans and other mammals