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Tobaz Brand names, Tobaz Analogs

Tobaz Brand Names Mixture

  • No information avaliable

Tobaz Chemical_Formula


Tobaz RX_link

Tobaz fda sheet

Tobaz msds (material safety sheet)

Tobaz Synthesis Reference

No information avaliable

Tobaz Molecular Weight

192.258 g/mol

Tobaz Melting Point

246-266 oC

Tobaz H2O Solubility

1.07E+004 mg/L

Tobaz State


Tobaz LogP


Tobaz Dosage Forms

400 mg and 600 mg tablets for oral administration

Tobaz Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Tobaz Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Tobaz Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Tobaz side effects and Toxicity

The oral LD50 of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Tobaz Patient Information

Tobaz Organisms Affected

Humans and other mammals