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Equizole Brand names, Equizole Analogs

Equizole Brand Names Mixture

  • No information avaliable

Equizole Chemical_Formula


Equizole RX_link


Equizole fda sheet

Equizole msds (material safety sheet)

Equizole Synthesis Reference

No information avaliable

Equizole Molecular Weight

192.258 g/mol

Equizole Melting Point

246-266 oC

Equizole H2O Solubility

1.07E+004 mg/L

Equizole State


Equizole LogP


Equizole Dosage Forms

400 mg and 600 mg tablets for oral administration

Equizole Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Equizole Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Equizole Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Equizole side effects and Toxicity

The oral LD50 of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Equizole Patient Information

Equizole Organisms Affected

Humans and other mammals