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Triasox Brand names, Triasox Analogs

Triasox Brand Names Mixture

  • No information avaliable

Triasox Chemical_Formula


Triasox RX_link

Triasox fda sheet

Triasox msds (material safety sheet)

Triasox Synthesis Reference

No information avaliable

Triasox Molecular Weight

192.258 g/mol

Triasox Melting Point

246-266 oC

Triasox H2O Solubility

1.07E+004 mg/L

Triasox State


Triasox LogP


Triasox Dosage Forms

400 mg and 600 mg tablets for oral administration

Triasox Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Triasox Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Triasox Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Triasox side effects and Toxicity

The oral LD50 of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Triasox Patient Information

Triasox Organisms Affected

Humans and other mammals