Nemacin en es it fr

Nemacin Brand names, Nemacin Analogs

Nemacin Brand Names Mixture

  • No information avaliable

Nemacin Chemical_Formula


Nemacin RX_link

Nemacin fda sheet

Nemacin msds (material safety sheet)

Nemacin Synthesis Reference

No information avaliable

Nemacin Molecular Weight

192.258 g/mol

Nemacin Melting Point

246-266 oC

Nemacin H2O Solubility

1.07E+004 mg/L

Nemacin State


Nemacin LogP


Nemacin Dosage Forms

400 mg and 600 mg tablets for oral administration

Nemacin Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, that, in the judgment of the physician, are life-threatening.

Nemacin Pharmacology

Tocainide is a primary amine analog of lidocaine with antiarrhythmic properties useful in the treatment of ventricular arrhythmias. Tocainide, like lidocaine, produces dose dependent decreases in sodium and potassium conductance, thereby decreasing the excitability of myocardial cells. In experimental animal models, the dose-related depression of sodium current is more pronounced in ischemic tissue than in normal tissue. Tocainide is a Class I antiarrhythmic compound with electrophysiologic properties in man similar to those of lidocaine, but dissimilar from quinidine, procainamide, and disopyramide.

Nemacin Absorption

Following oral administration, the bioavailability approaches 100 percent, and is unaffected by food.

Nemacin side effects and Toxicity

The oral LD50 of tocainide was calculated to be about 800 mg/kg in mice, 1000 mg/kg in rats, and 230 mg/kg in guinea pigs; deaths were usually preceded by convulsions.

Nemacin Patient Information

Nemacin Organisms Affected

Humans and other mammals