Ketohydroxyoestrin
Brand names,
Ketohydroxyoestrin
Analogs
Ketohydroxyoestrin
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Ketohydroxyoestrin
Chemical_Formula
C18H22O2
Ketohydroxyoestrin
RX_link
No information avaliable
Ketohydroxyoestrin
fda sheet
Ketohydroxyoestrin
msds (material safety sheet)
Ketohydroxyoestrin
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Ketohydroxyoestrin
Molecular Weight
270.366 g/mol
Ketohydroxyoestrin
Melting Point
254.5-256 oC
Ketohydroxyoestrin
H2O Solubility
3 g/100mL
Ketohydroxyoestrin
State
Solid
Ketohydroxyoestrin
LogP
4.067
Ketohydroxyoestrin
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Ketohydroxyoestrin
Indication
For management of Menopausal and postmenopausal disorders
Ketohydroxyoestrin
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Ketohydroxyoestrin
Absorption
43%
Ketohydroxyoestrin
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Ketohydroxyoestrin
Patient Information
Ketohydroxyoestrin
Organisms Affected
Humans and other mammals