Oestroform
Brand names,
Oestroform
Analogs
Oestroform
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Oestroform
Chemical_Formula
C18H22O2
Oestroform
RX_link
No information avaliable
Oestroform
fda sheet
Oestroform
msds (material safety sheet)
Oestroform
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Oestroform
Molecular Weight
270.366 g/mol
Oestroform
Melting Point
254.5-256 oC
Oestroform
H2O Solubility
3 g/100mL
Oestroform
State
Solid
Oestroform
LogP
4.067
Oestroform
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Oestroform
Indication
For management of Menopausal and postmenopausal disorders
Oestroform
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Oestroform
Absorption
43%
Oestroform
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Oestroform
Patient Information
Oestroform
Organisms Affected
Humans and other mammals