Estrusol
Brand names,
Estrusol
Analogs
Estrusol
Brand Names Mixture
- Cimicifuga Plex (Caulophyllum Thalictroides + Cimicifuga Racemosa + Copper + Cotton Plant + Estrone + Histamine Dihydrochloride + Hypothalamus + Magnesium Phosphate Dibasic + Pituitary Whole + Platinum + Sepia Officinalis L + Thyroid)
- Holis 98 (Dioscorea Vilosa + Estrone + Salvia + Saw Palmetto)
Estrusol
Chemical_Formula
C18H22O2
Estrusol
RX_link
No information avaliable
Estrusol
fda sheet
Estrusol
msds (material safety sheet)
Estrusol
Synthesis Reference
G. Anner, K. Miescher, and Helv. Chem. Acta. 31, 2173(1948)
Estrusol
Molecular Weight
270.366 g/mol
Estrusol
Melting Point
254.5-256 oC
Estrusol
H2O Solubility
3 g/100mL
Estrusol
State
Solid
Estrusol
LogP
4.067
Estrusol
Dosage Forms
Vaginal cream; Vaginal suppository; Patch; Skin gel; Tablet; IM injectable suspension
Estrusol
Indication
For management of Menopausal and postmenopausal disorders
Estrusol
Pharmacology
Estrone, a synthetically prepared or naturally occurring steroidal estrogen obtained from pregnant equine urine, is the primary circulating estrogen after menopause. Estrone is naturally derived from the peripheral conversion of androstenedione by an aromatase enzyme found in adipose tissues and is converted to estradiol in peripheral tissues. Estropipate is piperazine-stabilized estrone sulfate. Estrone, and estropipate are used to treat abnormalities related to gonadotropin hormone dysfunction, vasomotor symptoms, atrophic vaginitis, and vulvar atrophy associated with menopause, and for the prevention of osteoporosis due to estrogen deficiency.
Estrusol
Absorption
43%
Estrusol
side effects and Toxicity
Symptoms of overdose include nausea and vomiting. Withdrawal bleeding may occur in females.
Estrusol
Patient Information
Estrusol
Organisms Affected
Humans and other mammals